Best Bed Bug Spray For Killing Bed Bugs On Direct Contact

Ian Mutuli
Updated on
Ian Mutuli

Ian Mutuli

Founder and Managing Editor of Archute. He is also a graduate architect from The University of Nairobi, Kenya.
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Bed bugs can be really annoying. Before considering a pest control company, you may want to deal with these pesky insects by yourself. Having a bed bug spray can help you achieve this. Not only do they help protect you and your family, but they are also affordable.

You may also consider a bed bug spray when travelling. They act as repellants while you're in shuffling through different hostels or hotel rooms. They may not be as effective as bug sprays geared toward bed bug infestations, but they help keep your bed bug-free. Plus the most important thing is they give you peace of mind.

The best bed bug spray is convenient, easy to use and more affordable than professional treatments offered by pest control companies. You can find sprays that are naturally based while others contain insecticide. Those that are naturally based are safer to use are children and pets. All in all, you're looking for a spray that you can use on your beddings and furniture if need be.

We outlined the best bed bug sprays and factors to consider when buying them.

Best Bed Bug Sprays

1. EcoRaider Bed Bug Killer

Bed Bug Killer 16 oz EcoVenger by EcoRaider, 100% Kill...
  • PROVEN THROUGH USDA IR4 PHP PROGRAM — field tested by research...
  • EXTENDED DRY RESIDUAL PROTECTION — University study shows...
  • NON-TOXIC, SAFE AND ECO-FRIENDLY — certified USDA BioBased...

The bed bug spray is highly rated on Amazon and is considered to be the only natural product that kills bed bugs with 100% efficacy by the Journal of Entomology. It's the best bed bug spray if you're looking for a natural, non-toxic and safe formula you can use around pets and kids. The bed bug spray is a USDA BioBased insecticide, making it safe, and you can spray it directly on your mattresses, box springs, furniture, and carpets.

EcoRaider bed bug killer is made of all-natural, botanical ingredients and has a nice cedar/eucalyptus scent that dissipates quickly after application.

The EcoRaider bed bug killer is effective at eradicating all stages, including adult bed bugs and eggs. It can also kill bed bugs that have built up a resistance to traditional pesticides.

The spray provides extended protection for two weeks after application, even after dried. The 16-ounce bottle is easy to use and ideal for spraying into cracks and crevices where bed bugs hide.

You can also purchase a gallon jug size if you need to refill your bottle or anticipate a bigger job.


  • Natural formula.
  • Easy to use.
  • Smell dissipates quickly.
  • Effective bed killer.


  • Expensive.
  • Only effective for small bug problems.

2. Harris Bed Bug Killer

HARRIS White Label Bed Bug Killer, Liquid Spray with...
  • Kills Resistant Bed Bugs & Their Eggs - Kills even the toughest...
  • Kills Quickly - Knocks down bed bugs fast when sprayed directly
  • EPA Registered - Approved for use in homes with people and pets...
  • Long Residual - Continues to kill bed bugs for up to 16 weeks...
  • Odorless Formula - Odorless and non-staining formula will not...

The Harris Bed Bug Spray may be the best bed bug spray for you if you're sensitive to smells. The bed bug killer is an odourless formula; hence you won't need to worry about suffering through tough and strong insecticide smells. It also has a non-staining formula; thus, no damage will be caused when sprayed on your fabrics.

It comes either as a ready to go bottle or a gallon. The ready to go bottle is perfect for spot treatment allowing you to reach those cracks and crevices where bed bugs enjoy hiding. You can also use it on bed frames, box springs, inside empty dressers, furniture, closets, carpet edges and other furniture. The gallon is ideal if you require to spray a few rooms or plan to do multiple treatments.

The bed bug killer is effective at killing the toughest pyrethroid-resistant bed bugs and eggs on contact. The bug spray offers residual protection by killing bed bugs for up to 16 weeks after initial application.

The Bed bug killer is EPA( Environmental Protection Agency) registered, making it safe to use in homes with people and pets.


  • Easy to use.
  • Odourless.
  • Effective pyrethroid-resistant bed bugs killer.
  • Residual protection for up to 16 weeks.


  • Expensive.
  • Mattress treatment is limited to mattress seams, folds and edges.

3. Eco Defense Bed Bug Killer

Eco Defense Bed Bug Killer, Natural Organic Formula...
  • KILLS ON CONTACT - Natural, Organic, and Non Toxic ingredients...
  • NON STAINING - Won't stain your bedding like some products on the...
  • SLEEP SECURE - Made of completely natural, organic and non-toxic...
  • FASTEST TREATMENT - Eco Defense Bed Bug Killer Spray works...

Whether you have kids or pets or you prefer toxic-free products, regardless of your situation, the Eco Defense Bed Bug Killer is the best bed bug spray for those who prefer completely natural products.

The bed bug killer contains natural, organic and non-toxic ingredients. It's designed to eliminate bed bugs on contact in all stages of life, from eggs to adults.

The Eco Defense Bed Bug Killer has a pleasant smell once it dried. However, it does have a strong smell when you're spraying it. The bug killer can be applied directly to sheets, mattresses and covers and won't stain them.


  • Works well alongside diatomaceous earth.
  • Has residual protection.


  • Has a strong scent/odour- requires you to keep your windows open.
  • Requires continuous spraying.

4. Proof Bed Bug & Dust Mite Killer

Proof Bed Bug & Dust Mite Killer, Plant-Based Spray, 16...
  • KILL BED BUGS IN YOUR HOME - Our Most Advanced Formula - Targets...
  • EXTREMELY EFFECTIVE! - Can be used safely on your mattresses,...
  • LAB TESTED - Keeps killing adults for up to 2 weeks and eggs for...

The Proof bed bug killer has a plant-based formula that aims to eliminate the bed bugs at the source. The bug spray is the best bed bug spray if you are looking for multipurpose insecticide as it kills both bed bugs and dust mites. The bug spray kills on contact and offers residual protection of up to two weeks.

Its made from cold-pressed neem oil, which is known for its effectiveness in eliminating various bugs. The bug spray can be used on mattresses, curtains, carpets, furniture etc.


  • Offers residual protection of up to two weeks.
  • Kills both bed bugs and dust mites.
  • Plant-based formula - Uses neem oil.


  • Has strong smell.
  • Needs continuous spraying.

5. Rest Easy Bed Bug Spray

Rest Easy - Environmentally Friendly Bed Bug Spray -...
  • Environmentally Friendly Travel Bed Bug Spray by Rest Easy
  • All Natural, Non-Pesticide, Environmentally Friendly Green...
  • Safe around children and pets
  • Can kill other small insects, such as bed mites
  • Pleasant Cinnamon fragrance

While travelling, catching bed bugs is the last thing on your mind. However, having a bed bug spray can always come in handy, especially if you're worried that your accommodation may have these pesky little bugs.

As the name suggests, the Rest Easy Bed Bug Spray is the best bed bug spray to keep your mind at ease to help you ward off any bed bug infestations while on the road.

The spray comes in a perfect travel-sized 2-ounce bottle that will easily pass TSA(Transport Security Administration)-safety requirements. It will also not take up a lot of space in your luggage.

The spray has a pleasant cinnamon spray and is eco-friendly. It can be sprayed directly on bedding and the surrounding areas, including dresser drawers, closets, around headboards and baseboards of the hotel room before unpacking. It's an effective bed bug spray for mites as well.


  • Has a pleasant smell.
  • Compact size for travelling.
  • Works well as repellant.


  • Not effective for home pest control or as an insecticide.

Factors To Consider When Buying Best Bed Bug Sprays

a) Type

Bed bug sprays come in two forms: water-based or oil-based. The benefit of water-based sprays is that they generally won’t stain soft surfaces, making them the more common option on the market. They do, however, damage electronics, documents and wooden surfaces if used excessively.

Oil-based sprays can stain whatever they are sprayed on and tend to leave a sticky residue. This can, however, be removed with soap and water.

There are also powder treatments made from silica, such as Cimexa Insecticide Dust. These treatments work by drying out the exoskeleton of bed bugs and are often used along the baseboards of infested rooms.

b) Use

Most bed bug sprays can be used on various surfaces; hence, it's best to look for a formula and applicator best suited to your needs when looking for the best bed bug spray. Bed bug sprays are ideally designed to treat the nest site and bed frames, baseboards, furniture, draperies, and insects in other hiding places. It's common to find bed bug sprays that are specially designed for mattresses.

Bed bug sprays can also be used for furnishings, but it's worth noting that not all sprays can be used on mattresses due to the potency of various insecticides. Hence it's important to careful when purchasing them.

c) Ingredients

Most sprays contain powerful insecticides like pyrethroids to ensure the effective killing of bed bugs. When handling such products, it's important to follow the instructions of use carefully and take safety precautions to protect children and pets.

There's also the option of sprays with natural formula and plant-based oils like geranium oil. These tend to be more eco-friendly and safer to use around children and pets. However, they are not as strong as insecticides.

d) Eco-Friendliness

Though chemicals may help eliminate your bed bugs faster, there is the option of doing this in an eco-friendly way. Eco-friendly sprays are best suited for those with pets and children or those who prefer environmentally friendly products and free from chemicals. These products are free from toxins and tend to be made from natural and plant-based ingredients.

e) Odour

If you're sensitive to smells, this is worth noting, as bed bug sprays tend to have an odour. Some have a pleasant smell after they've dried, while other's will have a strong insecticide. This is something to look into while considering your spray, as it can determine if it's the best option for you.

f) Size

The size is particularly important if you're looking for travelling bug spray. You want a bottle that can fit into your luggage and that won't leak. The spray should be easy to use, portable, and, most importantly, comply with TSA(Transport Security Administration) requirements.

Frequently Asked Questions About Bed Bug Sprays (FAQs)

a) Do Bed Bug Sprays Really Work? 

When dealing with a bed bug infestation, the most frequently used ingredients are pyrethroids and pyrethrins. Pyrethroids are synthetic chemical insecticides, while pyrethrins are botanical insecticides developed from chrysanthemums. For effective pest control, it can be beneficial to use bed bug sprays that use multiple modes of attack as it increases the chances of using one that is effective on a specific type of bed bug.

b) How Do Bed Bug Sprays Work? 

After application, the ingredients act to kill bed bugs on contact by reducing their population and preventing reproduction. The best bed bug sprays effectively kill bed bug eggs, which is a key way to prevent bed bugs and shorten and infestation.

c) How Often Do You Have T Use Bed Bug Spray? 

Most bed bug sprays tend to offer treatments for up to 2 weeks. At the same time, some sprays extend protection for up to 16 weeks. Bed bug products like Silica-based bed bug powders can continue working for years as long as the powder remains dry. 

d) Where Can You Safely Use Bed Bug Spray?

When dealing with bed bug infestation, you generally need to treat your mattress, bed frame, baseboards, furniture, and any other areas where you’ve noticed you're being bitten.

Bed bugs prefer hidden areas rather than open, visible places, so spraying every inch of the surface area of your furniture is ideally not required.

It's important to note if a spray will be safe to use on items you will be in close contact with for an extended period of time. Most bed bug sprays tend to be safe for use on general household objects, but it's essential to read the label directions to be sure. Not all sprays are safe, while others have specific instructions on how to be used; for instance, they can be either sprayed on the entire mattress or the mattress seams. The directions will also show indicators of possible staining.

e) Are There DIY Pest Control Measures?

Some DIY Pest Control Measures that some people use include steam cleaning and washing their beddings and items in hot water at temperatures as high as 185 Fahrenheit. The notion is that this temperature kills bed bugs.

There's the use of diatomaceous earth, a silica-rich powder made from the sediment of fossilized algae. It kills bed bugs by destroying their exoskeleton.

You can also use traps designed to lure and kill bed bugs.

For a mild bed bug infestation, you can sprinkle baking soda around bedposts or spread crushed silica gel on the ground to create a barrier around your bedposts. This is commonly found in new shoe boxes and product shipment.

Ian Mutuli

About the author

Ian Mutuli

Founder and Managing Editor of Archute. He is also a graduate architect from The University of Nairobi, Kenya.
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